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Sunday, April 26, 2020

Malaria: Nigeria’s Annual Pandemic


26th April, 2020


By: Amir Abdulazeez

W
hen the decision was reached to spare a date for the observance of ‘World Malaria Day’ in May 2007 by the 60th session of the World Health Assembly, which is the World Health Organization's decision-making body, there were about 100 countries and territories that have eradicated Malaria, set the path for eradicating it or have reduced the disease to the barest or negligible level. In spite of this, Malaria was still regarded as a global disease, perhaps not for its spatial coverage, but for its high prevalence among a significant number of the global population mostly domiciled in Africa.

The World Malaria Day itself was an offshoot from the Africa Malaria Day, an event that had been observed since 2001 by African governments. The first World Malaria Day was held on 25th April, 2008 with the theme ‘Malaria: a disease without borders’. The day was established to provide education and understanding of malaria and spread information on annual implementation of national malaria-control strategies, including community-based activities for malaria prevention and treatment in endemic areas. Its observance served as a time to assess progress toward goals aimed at controlling malaria and reducing its mortality in affected countries.

A review of different reports suggests that globally, 3.3 billion people in 106 countries are at risk of malaria. In 2012, malaria caused an estimated 627,000 deaths, mostly among African children. Asia, Latin America, and to a lesser extent the Middle East and parts of Europe were also affected. According to the most recent World Malaria Report, the global tally of malaria reached 212 million new cases and 429,000 deaths in 2015. The rate of new malaria cases fell by 21% and death rates fell by 29% globally between 2010 and 2015. Children under 5 years of age are the most vulnerable group affected by malaria; in 2018, they accounted for 67% (272,000) of all malaria deaths worldwide. Malaria is the 3rd leading cause of death for children under five years worldwide, after pneumonia and diarrheal disease.

According to the latest World malaria report, released in December 2019, there were 228 million cases of malaria in 2018 compared to 231 million cases in 2017. The estimated number of malaria deaths stood at 405,000 in 2018, compared with 416,000 deaths in 2017. African continues to carry a disproportionately high share of the global malaria burden. In 2018, the region was home to 93% of all malaria cases and 94% of all malaria deaths. Malaria transmission is more intense in places where the mosquito lifespan is longer with the parasite getting adequate time to complete its development and having preference to bite humans rather than other animals. The long lifespan and strong human-biting habit of the African vector species is the main reason why approximately 90% of the world's malaria cases are in Africa. Thirty countries in Sub-Saharan Africa account for 90% of global malaria deaths.

How has Malaria been faring in Nigeria? In 2018, six countries accounted for more than half of all malaria cases worldwide: Nigeria (25%), the Democratic Republic of the Congo (12%), Uganda (5%), and Côte d’Ivoire, Mozambique and Niger (4% each). With this, Nigeria is the World Malaria Capital constituting a risk for 97% of Nigeria's population. The remaining 3% of the population are reported to only be relatively safe because they live on the highlands. According to the United States Embassy in Nigeria, there are an estimated 100 million malaria cases with over 300,000 deaths per year in Nigeria. This compares with 215,000 deaths per year in Nigeria from HIV/AIDS. Malaria is a major public health problem in Nigeria where it accounts for more cases and deaths than any other country in the world. This explains why the World Malaria Day is an important event in Nigeria.

Malaria is not the only deadly health challenge in Nigeria. According to various reports, the top causes of death in Nigeria are; malaria, lower respiratory infections, HIV/AIDS, diarrheal diseases, road injuries, protein-energy malnutrition, cancer, meningitis, stroke and tuberculosis. The Nigerian office of the International Center for Disease Control and Prevention listed the top 10 Causes of Death in Nigeria as at 2018 to be lower respiratory infections, neonatal disorders, HIV/AIDS, Malaria, diarrheal diseases, Tuberculosis, Meningitis, lschemic heart disease, Stroke and Cirrhosis. Researches have suggested that Malaria accelerates other diseases, including some of the ones mentioned above.

In most cases, malaria is transmitted through the bites of female Anopheles mosquitoes. According to WHO, there are more than 400 different species of Anopheles mosquito; around 30 are malaria vectors of major importance. All of the important vector species bite between dusk and dawn. The intensity of transmission depends on factors related to the parasite, the vector, the human host, and the environment. Anopheles mosquitoes lay their eggs in water, which hatch into larvae, eventually emerging as adult mosquitoes. The female mosquitoes seek a blood meal to nurture their eggs. Each species of Anopheles mosquito has its own preferred aquatic habitat; for example, some prefer small, shallow collections of fresh water, such as puddles and hoof prints, which are abundant during the rainy season in tropical countries.

Transmission also depends on climatic conditions that may affect the number and survival of mosquitoes, such as rainfall patterns, temperature and humidity. In many places, transmission is seasonal, with the peak during and just after the rainy season. Malaria epidemics can occur when climate and other conditions suddenly favour transmission in areas where people have little or no immunity to malaria. They can also occur when people with low immunity move into areas with intense malaria transmission, for instance to find work, or as refugees.

No matter how severe Malaria has become, it is time to eradicate it in Nigeria and all other places. Doing it is not rocket science provided sustainable and dedicated efforts are put in place. Globally, the elimination net is widening, with more countries moving towards the goal of zero malaria. In 2018, 27 countries reported fewer than 100 indigenous cases of the disease, up from 17 countries in 2010. The WHO Framework for Malaria Elimination (2017) provides a detailed set of tools and strategies for achieving and maintaining elimination. From 1999 to 2019, if Nigeria had a solid and implementable vision against Malaria, the disease may have been history by now. This would have eased the pressure on our health facilities and saved billions of Naira spent on drugs.

Countries that have achieved at least 3 consecutive years of 0 indigenous cases of malaria are eligible to apply for the WHO certification of malaria elimination. Over the last decade, 10 countries have been certified by the WHO Director-General as malaria-free: Morocco (2010), Turkmenistan (2010), Armenia (2011), Maldives (2015), Sri Lanka (2016), Kyrgyzstan (2016), Paraguay (2018), Uzbekistan (2018), Algeria (2019) and Argentina (2018). Some of these countries do not have half the resources that Nigeria commands.

Fighting and defeating Malaria even in advanced countries has not come without challenges. But the key issue is that prevention is always better than cure. Over the years, hundreds of millions of Insecticides Treated Nets have been distributed and used in most parts of Nigeria, yet the problem still persists. Sometimes, mosquitoes that transmit Malaria bite their victims before the bed time in which they might have been inside the nets. Therefore, they major way out is comprehensive town and environmental planning which will rehabilitate slums, poor unplanned settlements and stop the emergence of new ones. Government must rise up against the disease-breeding shanties we call settlements. Drainage network planning and rehabilitation is also essential.

One key control measure is vaccination. RTS,S/AS01 is the first and, to date, the only promising vaccine against severe malaria, in young African children. It acts against P.falciparum, the most deadly malaria parasite globally and the most prevalent in Africa. Among children who received 4 doses in large-scale clinical trials, the vaccine prevented approximately 4 in 10 cases of malaria over a 4-year period. This shows, even the vaccine is not a permanent ultimate solution. The WHO’s top advisory bodies for malaria and immunization have jointly recommended phased introduction of the vaccine in selected areas of sub-Saharan Africa. Three countries – Ghana, Kenya and Malawi – began introducing the vaccine in selected areas of moderate and high malaria transmission in 2019.

Eradicating Malaria can best be achieved first by individual and then community efforts. It is not a coincidence that the themes for the 2019 and 2020 World Malaria Days have been "Zero malaria starts with me". If we all make a resolve to take good care of our environment and personal hygiene, we stand a chance to defeat Malaria. Community efforts towards regularly sanitizing the environment and getting rid of stagnant waters through clearing of drainages and water ways is equally important. Community contributions for the periodic spray of insecticides will be far be better than sticking to the individual mosquito coils that drain our micro-economy. It is also far better than waiting to be infected and then spend hundreds or thousands on treatment.

The current efforts to defeat Malaria and other diseases by various stakeholders, even if inadequate yet, must be commended. Alongside the World Malaria Day, the WHO has dedicated days for seven other global public health campaigns; World Health Day, World Blood Donor Day, World Immunization Week, World Tuberculosis Day, World No Tobacco Day, World Hepatitis Day and World AIDS Day. With current developments, we may soon have World Coronavirus Day.

Twitter: @AmirAbdulazeez

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